Alternative Names:

SBLF, STN1; stoned B/TFIIA-alpha/beta-like factor, STON1, stoned B-like factor, stonin-1

Application:

WB

Reactivity:

Human,

Dilution:

WB 1:500-1:2000

	Western blot analysis on K562 cell lysate using STON1 Antibody

Purification:

Affinity-chromatography

Specificity:

STON1 Antibody detects endogenous levels of STON1

Immunogen:

A synthesized peptide derived from human STON1

Description:

Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane. This gene encodes one of two human homologs of the Drosophila melanogaster stoned B protein. This protein is related to components of the endocytic machinery and exhibits a modular structure consisting of an N-terminal proline-rich domain, a central region of homology specific to the human stoned B-like proteins, and a C-terminal region homologous to the mu subunits of adaptor protein (AP) complexes. Co-transcription of this gene and the neighboring downstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.