Alternative Names:

CK-14; CK14; cytokeratin 14; Cytokeratin-14; EBS3; EBS4; K14; K1C14; keratin 14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); Keratin, type I cytoskeletal 14; Keratin-14; KRT14; NFJ

Application:

WB IHC IF/ICC

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500

	Western blot analysis on NIH-3T3 cell lysate using Keratin 14 Antibody

Purification:

Affinity-chromatography

Specificity:

Keratin 14 Antibody detects endogenous levels of Keratin 14

Immunogen:

A synthesized peptide derived from human Keratin 14

Description:

K14 a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly. Generally associates with K5. Note: This description may include information from UniProtKB.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.