Alternative Names:

APO-1/CD95 (Fas)-associated phosphatase; DKFZp686J1497; FAP-1; Fas-associated phosphatase-1; Fas-associated protein-tyrosine phosphatase 1; hPTPE1; PNP1; protein tyrosine phosphatase 1E; protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas

Application:

WB IHC

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200

	Western blot analysis on LOVO cell lysate using FAP-1 Antibody

Purification:

Affinity-chromatography

Specificity:

FAP-1 Antibody detects endogenous levels of FAP-1

Immunogen:

A synthesized peptide derived from human FAP-1

Description:

PTPN13 Tyrosine phosphatase which regulates negatively FAS- induced apoptosis and NGFR-mediated pro-apoptotic signaling. Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily. Interacts with TRIP6 and TNFRSF6 (Fas receptor) through its second PDZ domain. Interacts with the C-terminal SVP motif of NGFR through its third PDZ domain.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.