Alternative Names:

EC 2.7.11.24; ERK-2; ERK2; ERT1; Extracellular signal- regulated kinase 2; Extracellular signal-regulated kinase 2; kinase ERK2; MAP kinase 2; MAPK; MAPK 2; MAPK1; Mitogen-activated protein kinase 1; Mitogen-activated protein kinase 2; MK01; p42-MAPK; P42

Application:

WB

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500-1:2000

	Western blot analysis on JK cell lysate using MAPK1/3 Antibody

Purification:

Affinity-chromatography

Specificity:

MAPK1/3 Antibody detects endogenous levels of MAPK1/3

Immunogen:

A synthesized peptide derived from human MAPK1/3

Description:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq]

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.