Alternative Names:

serum response factor

Application:

WB

Reactivity:

Human, Mouse,

Dilution:

WB 1:500-1:2000

	Western blot analysis on LOVO cell lysate using SRF Antibody

Purification:

Affinity-chromatography

Specificity:

SRF Antibody detects endogenous levels of SRF

Immunogen:

A synthesized peptide derived from human SRF

Description:

This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs).

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.