Alternative Names:

Ataxia telangiectasia mutated homolog; Ataxia telangiectasia mutated; kinase ATM

Application:

WB IF

Reactivity:

Human, Mouse

Dilution:

WB 1:500-1:1000 IHC 1:50-1:200

	Western blot analysis of extracts from 293T cells using ATM Antibody

Purification:

Affinity-chromatography

Specificity:

The antibody detects endogenous level of total ATM protein.

Immunogen:

Peptide sequence around aa.1979~1983 (E-G-S-Q-S) derived from Human ATM.

Description:

ATM encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.