Alternative Names:

PCL, FLT4 , FLT41, LMPH1A,

Application:

WB IHC IF

Reactivity:

Human, Mouse

Dilution:

WB 1:500-1:1000 IHC 1:50-1:200 IF 1:200

	Western blot analysis of extracts from HUVEC cells using VEGFR-3 Antibody (right) and the same antibody preincubated with blocking peptide

Purification:

Affinity-chromatography

Specificity:

The antibody detects endogenous level of total VEGFR-3 protein.

Immunogen:

Peptide sequence around aa.1279~1283 (L-A-S-E-E) derived from Human VEGFR-3.

Description:

Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.