Alternative Names:

Agpt2 antibody ANG 2 antibody ANG-2 antibody ANG2 antibody Angiopoietin 2a antibody Angiopoietin 2B antibody Angiopoietin-2 antibody Angiopoietin2 antibody ANGP2_HUMAN antibody ANGPT 2 antibody Angpt2 antibody Tie2 ligand antibody

Application:

WB IHC

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200

	Western blot analysis of ANG 2 expression in HUVEC cell lysate

Purification:

Affinity-chromatography

Specificity:

ANG 2 Antibody detects endogenous levels of total ANG 2

Immunogen:

A synthesized peptide derived from human ANG 2

Description:

Can induce tyrosine phosphorylation of TIE2. Binds to TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. Its function may be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.