Alternative Names:

Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1; Beta-1,3-glucuronyltransferase 1; Glucuronosyltransferase-P; GlcAT-P; UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase; GlcUAT-P; B3GAT1; GLCATP

Application:

IHC

Reactivity:

Human, Mouse, Rat

Dilution:

IHC 1:50-1:200

	Immunohistochemistry analysis of CD57 antibody in paraffin-embedded human brain tissue.

Purification:

Affinity-chromatography

Specificity:

CD57 Antibody detects endogenous levels of total CD57

Immunogen:

A synthesized peptide derived from human CD57

Description:

Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.