Alternative Names:

C-C motif chemokine 5; Small-inducible cytokine A5; T-cell-specific protein RANTES; SIS-delta; T cell-specific protein P228; TCP228; Eosinophil-chemotactic cytokine; EoCP; CCL5; D17S136E; SCYA5

Application:

WB IHC

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200

	Immunohistochemistry analysis of RANTES antibody in paraffin-embedded human lung carcinoma tissue.

Purification:

Affinity-chromatography

Specificity:

RANTES Antibody detects endogenous levels of total RANTES

Immunogen:

A synthesized peptide derived from human RANTES

Description:

Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. Binds to CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.