Alternative Names:

ATP-binding cassette sub-family G member 2; Placenta-specific ATP-binding cassette transporter; Breast cancer resistance protein; Mitoxantrone resistance-associated protein; CD338 antigen; CDw338; ABCG2; ABCP; BCRP; BCRP1

Application:

WB IHC

Reactivity:

Human

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200

	Western blot analysis of ABCG2 expression in HT-29 cells

Purification:

Affinity-chromatography

Specificity:

ABCG2 Antibody detects endogenous levels of total ABCG2

Immunogen:

A synthesized peptide derived from human ABCG2

Description:

High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.