Alternative Names:

high mobility group AT-hook 1; High mobility group AT-hook protein 1; High mobility group protein A1; high mobility group protein HMG-I/HMG-Y; High mobility group protein-R; HMG-I(Y); HMG1; HMG3; HMGA1; HMGB1; HMGIY

Application:

WB

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500-1:2000

	Western blot analysis of HMGA1 expression in mouse brain tissue

Purification:

Affinity-chromatography

Specificity:

HMGA1 Antibody detects endogenous levels of total HMGA1

Immunogen:

A synthesized peptide derived from human HMGA1

Description:

HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.