Alternative Names:

GPRC1E; GRM5; Metabotropic glutamate receptor 5 precursor; MGLUR5; MGR5

Application:

WB IF

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500-1:1000 IF 1:200

	Western blot analysis of extracts from HT-29 cells, using GRM5 antibody.The lane on the left is treated with the synthesized peptide.

Purification:

Affinity-chromatography

Specificity:

GRM5 antibody detects endogenous levels of total GRM5 protein.

Immunogen:

A synthesized peptide derived from internal of human GRM5.

Description:

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.