Alternative Names:

C-X-C chemokine receptor type 4; CCR4; CD184 antigen; CXC-R4; CXCR-4; FB22; Fusin; HM89; LCR1; LESTR; Leukocyte-derived seven transmembrane domain receptor; NPYRL; SDF-1 receptor; Stromal cell- derived factor 1 receptor

Application:

WB IHC

Reactivity:

Human,Mouse,Rat

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200

	Western blot analysis of CXCR4 expression in K562 cells

Purification:

Affinity-chromatography

Specificity:

CXCR4 Antibody detects endogenous levels of total CXCR4

Immunogen:

A synthesized peptide derived from human CXCR4

Description:

Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.