Alternative Names:

NR1C1, PPAR-alpha, PPARA Peroxisome proliferator-activated receptor alpha

Application:

WB,IF

Reactivity:

Human,Mouse

Dilution:

WB 1:500-1:2000 IF 1:100-1:500

	Western blot analysis of PPAR-alpha expression in NIH 3T3 cell extracts

Purification:

Affinity-chromatography

Specificity:

PPAR-alpha Antibody detects endogenous levels of total PPAR-alpha

Immunogen:

A synthesized peptide derived from human PPAR-alpha

Description:

Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.