Alternative Names:

Receptor for advanced glycosylation end products; Advanced glycosylation end product-specific receptor; AGER; RAGE

Application:

WB IHC

Reactivity:

Human

Dilution:

WB 1:1000 IHC 1:50-1:200

Purification:

Affinity-chromatography

Specificity:

AGER（RAGE） Antibody detects endogenous levels of totalAGER（RAGE）

Immunogen:

A synthesized peptide

Description:

RAGE is a type 1 membrane protein that is found on the surface of endothelial cells, mononuclear phagocytes and vascular smooth muscle cells. Binding of AGEs to RAGE results in the induction of cellular oxidant stress and activation of the transcription factor NFκB.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.