Alternative Names:

ADRB2, ALK-5, Activin receptor-like kinase 5, EC 2.7.11.30, ESK2, SKR4, TGF-beta receptor type I precursor, TGF-beta type I receptor, TGF-betaR1, TGFR-1, TGFR1, kinase TGF-beta-R1, receptor R4

Application:

WB,IF

Reactivity:

Human,Mouse

Dilution:

WB 1:500-1:2000 IF 1:100-1:500

	Western blot analysis of TGF β Receptor I expression in HepG2 cells

Purification:

Affinity-chromatography

Specificity:

TGF β Receptor I Antibody detects endogenous levels of total TGF β Receptor I

Immunogen:

A synthesized peptide derived from human TGF β Receptor I

Description:

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.