Alternative Names:

PAR4, PRKC apoptosis WT1 regulator protein, PRKC, apoptosis, WT1, regulator, Par-4, WT1-interacting protein, prostate apoptosis response protein 4, prostate apoptosis response protein PAR-4, prostate apoptosis response-4 protein, transcriptional repressor

Application:

WB,IHC

Reactivity:

Human,Mouse,Rat

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200

	Western blot analysis of Prostate Apoptosis Response protein 4 expression in NIH/3T3 cells

Purification:

Affinity-chromatography

Specificity:

Prostate Apoptosis Response protein 4 Antibody detects endogenous levels of total Prostate Apoptosis Response protein 4

Immunogen:

A synthesized peptide derived from human Prostate Apoptosis Response protein 4

Description:

Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.