Alternative Names:

OSIL antibody Oxidative stress induced like antibody p60 antibody p62 antibody p62B antibody Paget disease of bone 3 antibody PDB 3 antibody PDB3 antibody

Application:

WB

Reactivity:

Human,Mouse,Rat

Dilution:

WB 1:500-1:2000

	Western blot analysis of P62/SQSTM1 expression inHeLa

Purification:

Affinity-chromatography

Specificity:

P62/SQSTM1 Antibody detects endogenous levels of total P62/SQSTM1

Immunogen:

A synthesized peptide derived from human P62/SQSTM1

Description:

Adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.