Alternative Names:

CAS; P120CAS; P120CTN; CTNND; p120

Application:

WB IHC ICC/IF IP

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:100 IP 1:30

	Western blot analysis of delta1 Catenin expression in HeLa cell lysate.
	Immunofluorescent analysis of MCF-7 cells, using delta 1 Catenin/p120 Catenin Antibody .

Purification:

Affinity-chromatography

Specificity:

delta 1 Catenin/p120 Catenin Antibody detects endogenous levels of total delta 1 Catenin/p120 Catenin

Immunogen:

A synthesized peptide derived from human delta 1 Catenin/p120 Catenin

Description:

Catenin δ-1 (p120 catenin) has an amino-terminal coiled-coil domain followed by a regulatory domain containing multiple phosphorylation sites and a central Armadillo repeat domain of ten linked 42-amino acid repeats. The carboxy-terminal tail has no known function. Catenin δ-1 fulfills critical roles in the regulation of cell-cell adhesion as it regulates E-cadherin turnover at the cell surface to determine the level of E-cadherin available for cell-cell adhesion.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.