Alternative Names:

FADD-like ICE; FLICE; ICE8; MACH; MCH5; MORT1-associated CED-3 homolog; CAP4; Caspase-8 precursor;

Application:

WB ICC/IF

Reactivity:

Human

Dilution:

WB 1:500~1:2000 ICC/IF 1:50~1:100

	Western blot analysis of Caspase-8 expression in(1) Jurkat cell lysate; (2)HeLa cell lysate.
	Immunofluorescent analysis of K562cells, using Caspase-8 Antibody .

Purification:

Affinity-chromatography

Specificity:

Caspase-8 Antibody detects endogenous levels of total Caspase-8

Immunogen:

A synthesized peptide derived from human Caspase-8

Description:

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.