Alternative Names:

NF-kappa-B1; p84/NF-kappa-B1 p98; NFKB1; DNA-binding factor KBF1; EBP-1; NFkB-p50;

Application:

WB IHC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200

	Western blot analysis of NF-κB (p105/p50) expression in (1)PC-12 cell lysate;(2) NIH/3T3 cell lysate.
	Immunohistochemical analysis of paraffin-embedded human kidney, using NF-κB (p105/p50) Antibody.

Purification:

Affinity-chromatography

Specificity:

NF-κB (p105/p50) Antibody detects endogenous levels of total NF-κB (p105/p50)

Immunogen:

A synthesized peptide derived from human NF-κB (p105/p50)

Description:

NFkB-p105 a transcription factor of the nuclear factor-kappaB ( NFkB) group. Undergoes cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of NFkB. NFkB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.