Alternative Names:

ABP-280; ABPX; actin binding protein 280; Alpha-filamin; filamin 1; filamin A, alpha; FLN1; FLNA; FMD; MNS; NHBP; Non-muscle filamin; OPD; OPD1;

Application:

WB IHC ICC/IF FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:1000~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:100 FC 1:50

	Western blot analysis of Filamin A expression in (1) NIH/3T3 cell lysate;(2) Hela cell lysate.

Purification:

Affinity-chromatography

Specificity:

Filamin A antibody detects endogenous levels of total Filamin A

Immunogen:

A synthesized peptide derived from human Filamin A

Description:

Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.