Alternative Names:

Oligo2; bHLHb1; Class E basic helix-loop-helix protein 19; bHLHe19; OLIG2; BHLHB1; BHLHE19; PRKC;

Application:

WB IHC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200

	Western blot analysis of Olig2 in Human oligodendroglioma lysate.
	Immunohistochemical analysis of paraffin-embedded human mouse brain, using Olig2 Antibody.

Purification:

Affinity-chromatography

Specificity:

Olig2 Antibody detects endogenous levels of total Olig2

Immunogen:

A synthesized peptide derived from human Olig2

Description:

Olig2 is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.