Alternative Names:

PP-1A; PP-1B; PP1A; PP1alpha; PP1B; PP1beta; PPP1A; PPP1CD

Application:

WB IHC ICC/IF IP

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

	Western blot analysis of PPP1CA + PPP1CB expression in (1) Jurkat cell lysate; (2) HeLa cell lysate.
	Immunohistochemical analysis of paraffin-embedded human pancreas, using PPP1CA+PPP1CB Antibody.

Purification:

Affinity-chromatography

Specificity:

PPP1CA + 1CB Antibody detects endogenous levels of total PPP1CA + 1CB

Immunogen:

A synthesized peptide derived from human PPP1CA + 1CB

Description:

Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.