Alternative Names:

Inositol polyphosphate-5-phosphatase of 145 kDa; inositol polyphosphate-5-phosphatase, 145kDa; INPP5D; p150Ship;

Application:

WB IHC IP FC

Reactivity:

Human

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50 FC 1:50

	Western blot analysis of SHIP1 expression in Daudi cell lysate.
	Immunohistochemical analysis of paraffin-embedded rat spleen, using SHIP Antibody.

Purification:

Affinity-chromatography

Specificity:

SHIP Antibody detects endogenous levels of total SHIP

Immunogen:

A synthesized peptide derived from human SHIP

Description:

SHIP an SH2-containing inositol phosphatase. A hemopoietic-specific phosphatase that regulates cell survival, growth, cell cycle arrest and apoptosis. Hydrolyzes Ins(1,3,4,5)P4 and PtdIns(3,4,5)P3. A cytosolic protein with a SH2 domain in its N-terminus and two NPXY Shc binding motifs at its C-terminus.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.