Alternative Names:

KIAA0057;TRAM like protein;Tram2;Translocating chain associating membrane protein 2;Translocation associated membrane protein 2

Application:

WB

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000

	Western blot analysis of TRAM2 expression in HepG2 cell lysate.

Purification:

Affinity-chromatography

Specificity:

TRAM2 Antibody detects endogenous levels of total TRAM2

Immunogen:

A synthesized peptide derived from human TRAM2

Description:

TRAM2 is necessary for collagen type I synthesis. May couple the activity of the ER Ca2+ pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca2+ concentration at the site of collagen synthesis, and a high Ca2+ concentration may be necessary for the function of molecular chaperones involved in collagen folding.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.