Alternative Names:

p150/95 integrin alpha chain; Leu M5; SLEB6; ITGAX; CD11c; p150;Myeloid membrane antigen alpha subunit; Leukocyte surface antigen p150 95 alpha subunit; Integrin alpha-X;

Application:

WB IHC ICC/IF IP

Reactivity:

Human

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

	Western blot analysis of CD11c expression in THP-1 cell lysate treated with TPA.
	Immunohistochemical analysis of paraffin-embedded human spleen, using CD11c Antibody.

Purification:

Affinity-chromatography

Specificity:

CD11c Antibody detects endogenous levels of total CD11c

Immunogen:

A synthesized peptide derived from human CD11c

Description:

Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.