Alternative Names:

CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6;

Application:

WB IHC ICC/IF IP FC

Reactivity:

Human

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50

	Western blot analysis of CD11b expression in TF1 cell lysate.
	Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using CD11b Antibody.

Purification:

Affinity-chromatography

Specificity:

CD11b Antibody detects endogenous levels of total CD11b

Immunogen:

A synthesized peptide derived from human CD11b

Description:

ITGAM, also named as CD11B and CR3A, belongs to the integrin alpha chain family. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. ITGAM is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.