Alternative Names:

MERL; moesin-ezrin-radizin-like protein; neurofibromatosis type 2 gene; neurofibromatosis-2; Neurofibromin 2; NF-2; NF2; SCH; Schwannomerlin; schwannomerlin; Schwannomin

Application:

WB

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500-1:2000

	Western blot analysis of Merlin expression in IFN-α treated HuvEc whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

Purification:

Affinity-chromatography

Specificity:

Merlin Antibody detects endogenous levels of total Merlin

Immunogen:

A synthesized peptide derived from human Merlin

Description:

This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.