Alternative Names:

GTPase activating protein, GTPase activating protein ID-GAP, MGCRACGAP variant alpha, MGCRACGAP variant beta, RAC GTPase- activating protein 1, RAC GTPase-activating protein, RACGAP1

Application:

WB IF/ICC

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500-1:2000 IF/ICC 1:100-1:500

	Western blot analysis of GTPase Activating Protein expression in COS7 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

Purification:

Affinity-chromatography

Specificity:

GTPase Activating Protein Antibody detects endogenous levels of total GTPase Activating Protein

Immunogen:

A synthesized peptide derived from human GTPase Activating Protein

Description:

Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO (see MIM 165370), RAC (see RAC1; MIM 602048), and CDC42 (MIM 116952). GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.