Alternative Names:

Low-density lipoprotein receptor-related protein 2; LRP-2; Glycoprotein 330; gp330; Megalin; LRP2; DBS;

Application:

WB

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000

	Western blot analysis of Lrp2 expression in 293T cell lysate.

Purification:

Affinity-chromatography

Specificity:

Lrp2 / Megalin Antibody detects endogenous levels of total Lrp2 / Megalin

Immunogen:

A synthesized peptide derived from human Lrp2 / Megalin

Description:

LRP2, also named as gp330 and Megalin, belongs to the LDLR family. It acts together with cubilin to mediate HDL endocytosis. LRP2 may participate in regulation of parathyroid-hormone and para-thyroid-hormone-related protein release. Defects in LRP2 are the cause of Donnai-Barrow syndrome (DBS). The antibody is specific to LRP2.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.