Alternative Names:

CRK1; CSAID binding protein; CSBP; CSBP1; CSBP2; Cytokine suppressive anti- inflammatory drug binding protein; EC 2.7.11.24; MAP kinase MXI2; MAP kinase p38; MAPK14;

Application:

WB ICC/IF IP FC ChIP

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50 FC 1:30 ChIP 1:50

	Western blot analysis of p38 expression in (1) HeLa cell lysate; (2) NIH/3T3cell lysate; (3) PC-12 cell lysate.
	Immunofluorescent analysis of Hela cells, using p38 Antibody .

Purification:

Affinity-chromatography

Specificity:

p38 Antibody detects endogenous levels of total p38

Immunogen:

A synthesized peptide derived from human p38

Description:

Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.