Alternative Names:

FH ; FHC ; LDL receptor; LDLCQ2; LDLR ; Low Density Lipoprotein Receptor; Low density lipoprotein receptor class A domain containing protein 3;

Application:

WB ICC/IF FC

Reactivity:

Human Mouse

Dilution:

WB 1:1000~1:2000 ICC/IF 1:50~1:200 FC 1:50

	Western blot analysis of LDLR expression in HepG2 cell lysate.
	Immunohistochemical analysis of paraffin-embedded rat testis, using LDL Receptor Antibody .

Purification:

Affinity-chromatography

Specificity:

LDL Receptor Antibody detects endogenous levels of total LDL Receptor

Immunogen:

A synthesized peptide derived from human LDL Receptor

Description:

Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.