Alternative Names:

Cell cycle regulatory protein P95, NBN, NBS, NIBRIN, NIJMEGEN BREAKAGE syndrome protein 1, p95-NBS1

Application:

WB ICC/IF IP

Reactivity:

Human

Dilution:

WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50

	Western blot analysis of p95/NBS1 phosphorylation expression in Jurkat cell lysate treated with Etopside.

Purification:

Affinity-chromatography

Specificity:

Phospho-p95/NBS1 (S343) Antibody detects endogenous levels of total Phospho-p95/NBS1 (S343)

Immunogen:

A synthesized peptide derived from human Phospho-p95/NBS1 (S343)

Description:

NBS1 is a member of the MRE11/RAD50 double-strand break repair complex. Involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. Mutation results in the Nijmegen breakage syndrome (NBS), an autosomal recessive chromosomal instability syndrome.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.