Alternative Names:

NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA;

Application:

WB IHC ICC/IF IP FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:30

	Western blot analysis of TrkA expression in Human fetal brain tissue lysate.
	Immunohistochemical analysis of paraffin-embedded human liver, using TrkA Antibody.

Purification:

Affinity-chromatography

Specificity:

TrkA Antibody detects endogenous levels of total TrkA

Immunogen:

A synthesized peptide derived from human TrkA

Description:

The family of Trk receptor tyrosine kinases consists of TrkA, TrkB, and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. Neurotrophin signaling through these receptors regulates a number of physiological processes, such as cell survival, proliferation, neural development, and axon and dendrite growth and patterning.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.