Alternative Names:

CaMK II; CAMK2; Calcium/calmodulin-dependent protein kinase type II subunit beta; CaM kinase II subunit beta; CaMK-II subunit beta; CAMK2B; CAM2; CAMKB;

Application:

WB IHC ICC/IF

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

	Western blot analysis of CaMKII expression in (1)Mouse brain tissue lysate ;(2)Rat brain tissue lysate.
	Immunohistochemical analysis of paraffin-embedded mouse colon, using CaMKII Antibody.
	Immunofluorescent analysis of PC-12 cells, using CaMKII Antibody .

Purification:

Affinity-chromatography

Specificity:

CaMKII Antibody detects endogenous levels of total CaMKII

Immunogen:

A synthesized peptide derived from human CaMKII

Description:

CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.