Alternative Names:

GUD; AWT1; WAGR; WT33; NPHS4; WIT-2; EWS-WT1;

Application:

WB IHC ICC/IF FC

Reactivity:

Human Mouse

Dilution:

WB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

	Western blot analysis of WT1 expression in K562 cell lysate.
	Immunohistochemical analysis of paraffin-embedded mouse kidney, using Wilms Tumor Protein Antibody.

Purification:

Affinity-chromatography

Specificity:

Wilms Tumor Protein Antibody detects endogenous levels of total Wilms Tumor Protein

Immunogen:

A synthesized peptide derived from human Wilms Tumor Protein

Description:

Has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.