Alternative Names:

TSPO; PBR; BZRP; IBP; MBR; PKBS; Mitochondrial benzodiazepine receptor; Peripheral benzodiazepine receptor;

Application:

WB IHC ICC/IF IP FC

Reactivity:

Human Mouse

Dilution:

WB 1:5000~1:10000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50

	Western blot analysis of Calreticulin expression in (1) U87-MG cell lysate; (2) A431 cell lysate.
	Immunohistochemical analysis of paraffin-embedded human colon, using PBR Antibody .

Purification:

Affinity-chromatography

Specificity:

PBR Antibody detects endogenous levels of total PBR

Immunogen:

A synthesized peptide derived from human PBR

Description:

Peroxisome proliferator perfluordecanoic acid (PFDA) inhibits the Leydig cell steroidogenesis by affecting PBR mRNA stability, thus inhibiting PBR expression, cholesterol transport into the mitochondria and subsequent steroid formation. A cytoplasmic protein, PRAX-1 （peripheral benzodiazepine receptor-associated protein 1), is found to specifically interact with PBR.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.