Alternative Names:

p60-Src; c-Src; pp60c-src; Avian sarcoma virus; Proto-oncogene c-Src; SRC Oncogene;

Application:

WB FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 FC 30

	Western blot analysis of Phospho-Src (Y419) expression in A431 cell lysate treated with pervanadate.

Purification:

Affinity-chromatography

Specificity:

Phospho-Src (Y419) Antibody detects endogenous levels of total Phospho-Src (Y419)

Immunogen:

A synthesized peptide derived from human Phospho-Src (Y419)

Description:

Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.