Alternative Names:

Caspase-2; Caspase 2; Caspase2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1; CASP2; ICH1; NEDD2

Application:

WB IHC ICC/IF FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~2000 IHC 50~200 ICC/IF 50~200

	Western blot analysis of Caspase-2 expression in Jurkat cell lysate.
	Immunohistochemical analysis of paraffin-embedded mouse testis, using Caspase-2 Antibody.
	Immunofluorescent analysis of Hela cells, using Caspase-2 Antibody.

Purification:

Affinity-chromatography

Specificity:

Caspase-2 Antibody detects endogenous levels of total Caspase-2

Immunogen:

A synthesized peptide derived from human Caspase-2

Description:

Caspase-2 (Nedd2, ICH-1) is an aspartate-specific cysteine protease that is activated in response to various apoptotic stimuli. Caspase-2 is unique among the caspases in that it has features of both upstream caspases (long prodomain) and downstream caspases (DEXD substrate specificity). Caspase-2 is highly expressed in the brain during development and is expressed at low levels in adult tissue.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.