Alternative Names:

Apopain precursor; CASP-3; CPP-32; CPP32; Caspase-3; Cysteine protease CPP32; ICE3; SCA-1; SREBP cleavage activity 1;

Application:

WB IHC IP

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50

	Western blot analysis of Calreticulin expression in (1) Jurkat cell lysate; (2) COLO cells lysate.
	Immunohistochemical analysis of paraffin-embedded human stomach, using active + pro Caspase 3 Antibody .

Purification:

Affinity-chromatography

Specificity:

active + pro Caspase 3 Antibody detects endogenous levels of total active + pro Caspase 3

Immunogen:

A synthesized peptide derived from human active + pro Caspase 3

Description:

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.