Alternative Names:

H3 histone family, member A; H3/A; H31; H3FA; H3FB; H3FC; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; HIST1H3A; HIST1H3B; HIST1H3C; HIST1H3D; HIST1H3E;

Application:

WB ICC/IF

Reactivity:

Human Mouse

Dilution:

WB 1:500~1:2000 ICC/IF 1:50~1:200

	Western blot analysis of Histone H3 (acetyl K4) expression in HeLa+TSA cell lysate.

Purification:

Affinity-chromatography

Specificity:

Histone H3 (acetyl K4) Antibody detects endogenous levels of total Histone H3 (acetyl K4)

Immunogen:

A synthesized peptide derived from human Histone H3 (acetyl K4)

Description:

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.