Alternative Names:

AR; Androgen receptor splice variant 3; AR-V7(AR3);

Application:

WB IHC

Reactivity:

Human

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200

	Western blot analysis of Androgen Receptor expression in 22Rv1 cell lysate.
	Immunohistochemical analysis of paraffin-embedded human prostate carcinoma, using Androgen Receptor(AR-V7 specific) Antibody.

Purification:

Affinity-chromatography

Specificity:

Androgen Receptor(AR-V7 specific) Antibody detects endogenous levels of total Androgen Receptor(AR-V7 specific)

Immunogen:

A synthesized peptide derived from human Androgen Receptor(AR-V7 specific)

Description:

Belongs to the nuclear hormone receptor family. Contains nuclear receptor DNA-binding domain. Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. This target is a splice variant of Androgen receptor (UniProt P10275) lacking the C-terminal androgen binding site.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.