Alternative Names:

39.1; CK-17; Cytokeratin-17; K17; K1C17; keratin 17; Keratin, type I cytoskeletal 17; Keratin-17; KRT17; PC; PC2; PCHC1;

Application:

WB IHC ICC/IF FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:30

	Western blot analysis of Cytokeratin 17 expression in HACAT cell lysate.
	Immunohistochemical analysis of paraffin-embedded human tonsil, using Cytokeratin 17 Antibody.
	Immunofluorescent analysis of Hela cells, using Cytokeratin 17 Antibody .

Purification:

Affinity-chromatography

Specificity:

Cytokeratin 17 Antibody detects endogenous levels of total Cytokeratin 17

Immunogen:

A synthesized peptide derived from human Cytokeratin 17

Description:

Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.