Alternative Names:

PHB; PHB1; HEL 215; Epididymis secretory sperm binding protein Li 54e;

Application:

WB IHC ICC/IF IP FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30 FC 1:30

	Western blot analysis of Prohibitin expression in Ramos cell lysate.
	Immunohistochemical analysis of paraffin-embedded human kidney, using Prohibitin Antibody.

Purification:

Affinity-chromatography

Specificity:

Prohibitin Antibody detects endogenous levels of total Prohibitin

Immunogen:

A synthesized peptide derived from human Prohibitin

Description:

PHB1 is 30kDa tumor suppressor protein involved in cell cycle control. PHB1 has been found in mitochondria, the nucleus and the plasma membrane, as well as extracellularly in circulation. In mitochondria prohibitins mainly exist as membrane-bound ring complexes and function as chaperones maintaining mitochondrial protein stability during protein synthesis and transportation.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.