Alternative Names:

BP180; BPA 2; BPAG2; COL17A1; Collagen 17; CollagenXVII; LAD1

Application:

WB IHC ICC/IF IP

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30

	Western blot analysis of Collagen XVII expression in Human skin lysate.
	Immunohistochemical analysis of paraffin-embedded mouse skin, using Collagen XVII Antibody.
	Immunofluorescent analysis of A431 cells, using Collagen XVII Antibody .

Purification:

Affinity-chromatography

Specificity:

Collagen XVII Antibody detects endogenous levels of total Collagen XVII

Immunogen:

A synthesized peptide derived from human Collagen XVII

Description:

May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane. The 120 kDa linear IgA disease antigen is an anchoring filament component involved in dermal-epidermal cohesion. Is the target of linear IgA bullous dermatosis autoantibodies.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.