Alternative Names:

HIST1H2AB; Histone H2A type 1-B/E; Histone H2A.2; Histone H2A/a; Histone H2A/m; H2AFM;

Application:

WB IHC ICC/IF

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

	Western blot analysis of Histone H2A.Z expression in (1)Neuro-2a cell lysate;(2)HeLa cell lysate.
	Immunohistochemical analysis of paraffin-embedded human kidney, using Histone H2A.Z Antibody.

Purification:

Affinity-chromatography

Specificity:

Histone H2A.Z Antibody detects endogenous levels of total Histone H2A.Z

Immunogen:

A synthesized peptide derived from human Histone H2A.Z

Description:

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.