Alternative Names:

HK1;HK1-ta;HK1-tb;HK1-tc;HKI;HXK1; Hexokinase 1;

Application:

WB IHC ICC/IF FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:200

	Western blot analysis of Hexokinase 1 expression in (1) MCF-7 cell lysate; (2) 293T cell lysate.
	Immunohistochemical analysis of paraffin-embedded human lung carcinoma, using Hexokinase 1 Antibody.

Purification:

Affinity-chromatography

Specificity:

Hexokinase 1 Antibody detects endogenous levels of total Hexokinase 1

Immunogen:

A synthesized peptide derived from human Hexokinase 1

Description:

Hexokinases I, II, and III are associated with the outer mitochondrial membrane and are critical for maintaining an elevated rate of aerobic glycolysis in cancer cells (Warburg Effect) in order to compensate for the increased energy demands associated with rapid cell growth and proliferation.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.