Alternative Names:

HSP 90; HSP90A; HSP90B; LAP-2; HSPC1; HSPC2;

Application:

WB IHC ICC/IF IP FC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:5000~1:10000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:100

	Western blot analysis of Hsp90 expression in (1) HeLa cell lysate; (2) Jurkat cell lysate; (3) RAW264.7 cell lysate; (4) NIH/3T3 cell lysate; (5) PC-12 cell lysate; (6) C6 cell lysate.
	Immunohistochemical analysis of paraffin-embedded human liver carcinoma, using Hsp90 Antibody .
	Immunofluorescent analysis of Hela cells, using Hsp90 Antibody.

Purification:

Affinity-chromatography

Specificity:

Hsp90 Antibody detects endogenous levels of total Hsp90

Immunogen:

A synthesized peptide derived from human Hsp90

Description:

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.